Peter K Todd Selected Research

5' Untranslated Regions (5' UTR)

1/2022	Mechanistic convergence across initiation sites for RAN translation in fragile X associated tremor ataxia syndrome.
1/2019	DDX3X and specific initiation factors modulate FMR1 repeat-associated non-AUG-initiated translation.
1/2018	Repeat-associated non-AUG (RAN) translation and other molecular mechanisms in Fragile X Tremor Ataxia Syndrome.
1/2017	Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.
8/2015	RAN translation at CGG repeats induces ubiquitin proteasome system impairment in models of fragile X-associated tremor ataxia syndrome.
10/2014	TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1.
1/2014	Fragile X mental retardation protein expression in Alzheimer's disease.
5/2013	CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome.
3/2013	Sequestration of DROSHA and DGCR8 by expanded CGG RNA repeats alters microRNA processing in fragile X-associated tremor/ataxia syndrome.
3/2013	Impaired activity-dependent FMRP translation and enhanced mGluR-dependent LTD in Fragile X premutation mice.

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Peter K Todd Research Topics

Disease

25	Fragile X Tremor Ataxia Syndrome 12/2022 - 03/2010
17	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2022 - 03/2010
5	Fragile X Syndrome (Martin Bell Syndrome) 01/2021 - 02/2003
5	Myotonic Dystrophy (Dystrophia Myotonica) 01/2021 - 03/2010
4	Frontotemporal Dementia (Semantic Dementia) 01/2021 - 10/2014
3	Neoplasms (Cancer) 01/2022 - 01/2019
3	Intellectual Disability (Idiocy) 01/2021 - 02/2003
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2021 - 10/2014
1	Dysbiosis 01/2022
1	Inflammation (Inflammations) 01/2022
1	Colonic Neoplasms (Colon Cancer) 01/2022
1	COVID-19 01/2022
1	Colorectal Neoplasms (Colorectal Cancer) 01/2022
1	Guillain-Barre Syndrome 01/2022
1	Huntington Disease (Huntington's Disease) 01/2021
1	Ataxia (Dyssynergia) 01/2021
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 10/2014
1	Nervous System Diseases (Neurological Disorders) 10/2014
1	Infections 04/2014
1	Cerebellar Ataxia (Dysmetria) 04/2014
1	Alzheimer Disease (Alzheimer's Disease) 01/2014
1	Proteostasis Deficiencies 05/2012

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2010
11	5' Untranslated Regions (5' UTR)IBA 01/2022 - 12/2010
9	RNA (Ribonucleic Acid)IBA 01/2022 - 03/2010
5	Peptides (Polypeptides)IBA 01/2022 - 01/2016
4	Messenger RNA (mRNA)IBA 01/2022 - 03/2010
4	NucleotidesIBA 12/2019 - 11/2011
4	Fragile X Mental Retardation ProteinIBA 01/2014 - 02/2003
3	UbiquitinIBA 10/2019 - 05/2013
3	Initiator Codon (Start Codon)IBA 01/2019 - 01/2016
3	RNA-Binding Proteins (RNA-Binding Protein)IBA 10/2014 - 02/2003
2	AntibodiesIBA 10/2019 - 12/2016
2	3' Untranslated Regions (3' UTR)IBA 11/2014 - 01/2014
1	GuanineIBA 12/2022
1	CytosineIBA 12/2022
1	Peptide Initiation Factors (Initiation Factor)IBA 01/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022
1	3-hydroxypropionaldehydeIBA 01/2022
1	polyglutamineIBA 01/2021
1	Eukaryotic Initiation FactorsIBA 01/2019
1	RNA Helicases (RNA Helicase)IBA 01/2019
1	polyprolineIBA 12/2016
1	Coloring Agents (Dyes)IBA 12/2016
1	polyalanineIBA 12/2016
1	ran GTP-Binding ProteinIBA 12/2016
1	RNA Precursors (Precursor, mRNA)IBA 01/2016
1	Proteasome Endopeptidase Complex (Proteasome)IBA 08/2015
1	Protein Kinases (Protein Kinase)IBA 11/2014
1	hnRNP A2IBA 10/2014
1	DNA-Binding Proteins (DNA Binding Protein)IBA 10/2014
1	Rituximab (Mabthera)FDA Link 04/2014
1	Natalizumab (Tysabri)FDA Link 04/2014
1	MicroRNAs (MicroRNA)IBA 03/2013
1	Histone Deacetylases (Histone Deacetylase)IBA 12/2010

Therapy/Procedure

2	Therapeutics 01/2022 - 04/2014
1	Liver Transplantation 01/2022